The Chronic Respiratory Disease Questionnaire (CRQ) is the most commonly used disease specific measurement tool to assess HRQL in patients with chronic . Due to their widespread and thorough validation, the following questionnaires are recommended: Chronic Respiratory Disease Questionnaire (CRDQ or CRQ) . To measure health related quality of life in patients with chronic respiratory disease.

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Based on these interviews, items were chroic on their importance and grouped into 1 of 4 categories: From these results, the researchers concluded that the CRQ has excellent reliability. Wijkstra et al 10 found that the internal consistency of the dyspnea domain to be much lower than the other 3.

Outcomes in Cardiopulmonary Physical Therapy: Chronic Respiratory Disease Questionnaire (CRQ)

HRQL is commonly assessed through self or interviewer administered questionnaires, and may be discriminative evaluating cross-sectional differences between patients cgronic a single point in time or evaluative measuring longitudinal changes within patients over a period of time.

Cardiopulm Phys Ther J. Singh et al 5 reported improvements in the treadmill endurance test were correlated to improvements in the CRQ total score and improvements in the domain scores of dyspnea, fatigue, and mastery. Construct validity refers to an instrument’s ability to measure the constructs, or abstract concepts, that it intends to measure. They administered the questionnaire 6 times in a 2-week interval to 25 patients with stable COPD.

CRQ – Chronic Respiratory Disease Questionnaire

The CRQ scores also follow predicted tracts and correlate well with clinical status. Another important characteristic of an chrknic tool is its ability to detect change. In the fatigue domain, which was not reliable as a questionnaiire, 3 of the 4 individual items showed insignificant correlation.

This indicates that the CRQ was able to detect the change in patient condition that occurred with treatment. Validity was determined to be strong; no statistically significant difference between the 2 instruments was found in the fatigue and mastery domains, and the small mean differences found in the dyspnea 0.


The 3 studies included: Eur Resp J Jan;25 1: With the development of the self-administered CRQ, validity of the newer instrument was established by comparing it to the gold standard of the original version. It is not strongly correlated with physiologic respiraatory related to dyspnea, indicating the need to administer HRQL tools alongside physiologic measures in order to gain the full picture of the patient’s disease state.

Many studies reported internal consistency of the questionnaire to be high over all domains 391319 with Cronbach’s alpha coefficients ranging from 0. The validity of the CRQ is strengthened by the study performed by Shawn et al 14 which found statistically significant differences in CRQ scores between patients who had a cfq of respiratpry pulmonary condition and those who did not.

Harper et al 13 also examined CRQ measurements in clinically stable patients over time.

In the emotional function domain, 2 of the 7 items were found to lack significant correlation. Wyrwich et al 29 described the importance of determining the physician’s definition of the MCID in order to better understand and support the use of HRQL measurement tools in the clinic. Other useful means of the measure are interpreting studies that show significant findings and improvement of expressing results.

This property can also aid researchers when gathering resources to conduct studies by enabling them to calculate appropriate sample sizes.

Assessing the minimal important differences in symptoms: According to the office of the developer, written communication, October, using the CRQ-IAS, in which the dyspnea section is also standardized, reduces the administration time to 8 minutes. It correlates well with other disease specific and generic measures of HRQL as well as with global ratings of change. The instrument consists of 20 questions scored on a 7-point Likert-type scale in four domains: From these results, the researchers concluded that the CRQ was responsive across all domains for detecting short-term changes.


The limited availability of literature regarding intra-rater and inter-rater reliability indicates the need for further research in these areas.

According to the office of the developer written communication, October, there are currently 4 different formats of the CRQ available for clinical use: Kirshner B, Guyatt G. Each domain includes 4 to 7 items, with each item graded on 7-point Likert scale; item scores within a domain are summated to provide a total score for each domain.

Chronic Respiratory Disease Questionnaire (CRQ)

In order for a questionnaire to be considered practical, it must assess what it claims to measure. Measuring health related quality of life. For Clinical Trial and Questionnire Study use, please fill out our request form from our website: The developers found that the CRQ scores at the follow-up assessment were, to a large extent, better than at the initial distribution of the questionnaire, even though spirometry values were only slightly improved.

Rutten-Van Molken et al 3 completed a study to determine the MCID using both methods of between patient comparison and within patient comparison. J Gen Intern Med. Guyatt et al 2 found that the CRQ has similar responsiveness to the Transitional Dyspnea Index and superior responsiveness to the Rand dyspnea questionnaire, the oxygen cost diagram, and the Rand physical and emotional function questionnaires.

Chronic Respiratory Disease Questionnaire-CRQ

Minimally clinically important difference MCID is a resource available to gauge if a patient deems intervention effective or not. Initial testing of reproducibility, responsiveness, and validity was also completed. The advantage of this version is that there is no requirement for presence of an interviewer during the completion of the questionnaire.